The authors of this article state that the present construct of schizophrenia that is outlined in the Diagnostic and Statistical Manual of Mental Disorders and International Classification of Diseases have strengths and weaknesses. While the strengths include the reliability of diagnosis and improved communication among clinicians and patients and their families, there are weaknesses that should be taken into account. The authors summarize these strengths and weaknesses and note that clinicians and researchers should be prepared to leave the present schizophrenia construct behind in the future. They explain that healthcare professionals should be urged to accompany the Diagnostic and Statistical Manual of Mental Disorders and International Classification of Diseases diagnosis with a more detailed clinical characterization of an individual, in addition to family history and comorbidities, among other factors.

Reference: Galderisi S, Giordano GM. We are not ready to abandon the current schizophrenia construct, but should be prepared to do so. Schizophr Res. 2022;242:30-34. doi:10.1016/j.schres.2021.12.007