The Psychopharmacology Algorithm Project at the Harvard South Shore Program provided an update of the schizophrenia algorithm from conducting a literature review. First-line, second monotherapy options, and third trial options are outlined.

Reference: Osser DN, Roudsari MJ, Manschreck T. The psychopharmacology algorithm project at the Harvard South Shore Program: an update on schizophrenia. Harv Rev Psychiatry. 2013;21(1):18-40. doi:10.1097/HRP.0b013e31827fd915